Company Analysis

BioCryst Pharmaceuticals, Inc. (BCRX)

Nasdaq: BCRX · Biological Products, (No Diagnostic Substances) · Durham, NC · filing with the SEC since 1995
Grade6.1
◀ Past 6.3● Present 5.6▶ Future 6.4

The grade of BioCryst Pharmaceuticals, Inc.

Nine metrics read from its own filings, by tense
Headline grade
6.1/10
◀ Past6.325% of the headline
● Present5.635% of the headline
▶ Future6.440% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

All nine metrics read as filed from the record.

◀ Past

What did they actually do?

6.3/1025% of the headline grade · 3 of 3 filed

Surviving crises

as filed
8.0/10

Has it survived what it has been through?

No warning events in its filings since 2017.

weight 22% of this tense · 80th percentile among 159 sector filers · read for itself

From the record

BioCryst Pharmaceuticals, Inc.'s filings since 2017 show no warning events in the scan: no bankruptcy or receivership notice, no debt default notice, no exchange listing notice, no restatement warning, no auditor change, no material cyber incident and no late-report notice (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
6.5/10

What has it actually done, year after year?

+47.6% a year over 10 filed years; profitable in 1 of 10.

weight 45% of this tense · 65th percentile among 102 sector filers · read for its customers

From the record

BioCryst Pharmaceuticals, Inc.'s 10 filed years say what it did: revenue went from $26 million in fiscal 2016 to $875 million in fiscal 2025, up 47.6% a year; it rose in 6 of 9 years; the deepest fall was 64% from fiscal 2019 to fiscal 2020; net income was positive in 1 of 10 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span47.6%top 29% of its family
  • the share of years revenue rosetop 36% of its family
  • the share of filed years with a profittop 35% of its family
  • the deepest fall from a revenue peak63.5%top 42% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

as filed
4.9/10

How has it treated the people who own it?

Share count grew 5.5% a year. 0% of cash flow returned. Insiders: 10 sales, 0 purchases.

weight 33% of this tense · 49th percentile among 21 sector filers · read for its shareholders

From the record

Over the 3 fiscal years to 2025-12-31, BioCryst Pharmaceuticals, Inc.'s diluted share count grew about 5.5% a year, and dividends and buybacks returned about 0% of its operating cash flow over 3 years (its filed statements). Its officers and directors filed 10 sales (8 under scheduled 10b5-1 plans) and 0 purchases of their own stock on the open market in the year to 2026-09-30 (their Form 4 filings).

What it rests on

  • the share count over the yearstop 26% of its family
  • cash returned against operating cash flowbottom 24% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

● Present

What are they doing right now?

5.6/1035% of the headline grade · 3 of 3 filed

Financial health

as filed
6.2/10

Is it financially healthy right now?

Leverage 123%: owes 123¢ per asset dollar.

weight 45% of this tense · 62nd percentile among 147 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-12-31, BioCryst Pharmaceuticals, Inc.'s shareholders' equity was below zero, so the profit on it is not read, and gross profitability: its products earned about 166 cents per dollar of everything the company owns (revenue less the cost of revenue). Leverage: it owed about 123 cents per dollar of assets, and net share issuance: its share count grew 5.7% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetsbottom 14% of its family
  • gross profit against assetstop 1% of its family
  • the share count against the year beforetop 28% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
8.7/10

How strong is its position in its industry?

top 14% of 102 in its family; net margin 30.2%.

weight 22% of this tense · 86th percentile among 102 sector filers · read for its customers

From the record

BioCryst Pharmaceuticals, Inc.'s standing among 102 graded names in its industry family: revenue of $875 million in fiscal 2025 ranks in the top 10% by size; a net margin of 30.2% ranks in the top 8%; revenue growth of 47.8% a year over the last 3 filed years ranks in the top 22% (its annual reports).

What it rests on

  • revenue against the family$875Mtop 10% of its family
  • net margin30.2%top 8% of its family
  • three-year revenue growth47.8%top 22% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
2.7/10

What are the people in charge doing?

bottom 27% of 110 in its family for leadership.

weight 33% of this tense · 27th percentile among 110 sector filers · read for its shareholders

From the record

BioCryst Pharmaceuticals, Inc.'s leadership, from its insiders' filings and its current reports: no one files under a chief executive's title, so that part is not read; the 14 officers and directors filing in the last fifteen months have been on the record a median of 5.2 years (bottom 43%); 14 officer or director changes were reported on Form 8-K since 2023-11-13, against the 14 people in charge now (bottom 11%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge14 in three years among 14 peoplebottom 11% of its family
  • the median years the people in charge have filed5.2 yearsbottom 43% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

6.4/1040% of the headline grade · 3 of 3 filed

Room to expand

as filed
5.5/10

How much room does it have to grow?

top 45% of 92 in its family for room to expand.

weight 33% of this tense · 55th percentile among 92 sector filers · read for itself

From the record

BioCryst Pharmaceuticals, Inc.'s room to grow, from the newest filed statements (fiscal 2025): cash of $90 million against debt of $0 thousand leaves 17.5% of its assets as net cash, bottom 30% of its family; cash from operations less capital spending is 39.4% of revenue (top 5%); a gross margin of 97.8% (top 18%); research spending of 19% of revenue (bottom 15%) (its annual report).

What it rests on

  • cash less debt against assets17.5%bottom 30% of its family
  • cash from operations less capital spending against revenue39.4%top 5% of its family
  • gross margin97.8%top 18% of its family
  • research spending against revenue19.0%bottom 15% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
6.4/10

What could actually drive growth from here?

top 36% of 100 in its family for growth drivers.

weight 45% of this tense · 64th percentile among 100 sector filers · read for its customers

From the record

BioCryst Pharmaceuticals, Inc.'s growth drivers, from the filed years to fiscal 2025: revenue grew 47.8% a year over the last three filed years against 47.6% over all 10, speeding up (top 28% of its family); the newest year grew 94.2% (top 22%); research spending grew -13.1% a year (bottom 24%); capital spending grew 22.2% a year (top 16%) (its annual reports). BioCryst Pharmaceuticals, Inc. reported 4 product lines in fiscal 2025: ORLADEYO at $602 million (68%), License at $244 million (28%), Other Income From Contract With Customer at $29 million (3%), and 1 more; 2 of 3 grew against the year before (its annual report).

What it rests on

  • three-year growth against the whole span+0.2 points a yeartop 28% of its family
  • the newest year's revenue growth94.2%top 22% of its family
  • three-year growth of research spending-13.1%bottom 24% of its family
  • three-year growth of capital spending22.2%top 16% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
7.5/10

Did its newest year beat what its own record pointed to?

top 25% of 72 in its family for expectations against reality.

weight 22% of this tense · 75th percentile among 72 sector filers · read for its shareholders

From the record

BioCryst Pharmaceuticals, Inc.'s newest year against its own record: revenue of $875 million in fiscal 2025 came in 50.5% above the $581 million its prior three years' pace pointed to (top 26% of its family); net income of $264 million against a prior three-year average of $188 million (top 5%); a net margin of 30.2% against -59.8% before (top 42%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace50.5%top 26% of its family
  • net income against the prior three years' average+241%top 5% of its family
  • net margin against its prior average+89.9 pointstop 42% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton BCRX · research, not advice