Company Analysis

Clene Inc. (CLNN)

Nasdaq: CLNN · Pharmaceutical Preparations · Salt Lake City, UT · filing with the SEC since 2020
Grade3.0
◀ Past 3.1● Present 3.1▶ Future 2.7
1 est.

The grade of Clene Inc.

Nine metrics read from its own filings, by tense
Headline grade
3.0/10
◀ Past3.125% of the headline
● Present3.135% of the headline
▶ Future2.740% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

Of the nine metrics, 8 read as filed from the record and 1 is an SI estimate, each with its reasoning, its confidence and what would change it on its card.

◀ Past

What did they actually do?

3.1/1025% of the headline grade · 2 of 3 filed, 1 estimated

Surviving crises

as filed
2.8/10

Has it survived what it has been through?

7 warning events since 2020; the latest 2025-05-07.

weight 22% of this tense · 27th percentile among 497 sector filers · read for itself

From the record

Clene Inc.'s filings since 2020 show 7 warning events of 2 kinds: a notice about its exchange listing (8-K item 3.01, 5 times, the latest 2025-05-07); an auditor change (8-K item 4.01, 2 times, the latest 2021-04-02) (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
3.0/10

What has it actually done, year after year?

-0.6% a year over 6 filed years; profitable in 0 of 6.

weight 45% of this tense · 30th percentile among 323 sector filers · read for its customers

From the record

Clene Inc.'s 6 filed years say what it did: revenue went from $206 thousand in fiscal 2020 to $200 thousand in fiscal 2025, down 0.6% a year; it rose in 2 of 5 years; the deepest fall was 72% from fiscal 2021 to fiscal 2025; net income was positive in 0 of 6 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span-0.6%bottom 28% of its family
  • the share of years revenue rosebottom 24% of its family
  • the share of filed years with a profitbottom 27% of its family
  • the deepest fall from a revenue peak72.3%bottom 43% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

SI estimate
3.3/10

How has it treated the people who own it?

SI estimate 3.3/10, confidence 35 of 100 (one part).

weight 33% of this tense · 33rd percentile among 464 sector filers · read for its shareholders

SI estimate Inferred, not read as filed

Why it is an estimate
Read from one part only, the share count over the years, which ranks in the bottom 33% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
What the record cannot read
Fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
How it was reasoned
one part: the share count over the years, the one part on file, ranked among 464 in its family.
Confidence
35 of 100
What would change it
A filing that carries the missing parts replaces this estimate with the filed reading.

From the record

SI estimate, not a filed reading: Clene Inc.'s shareholder treatment is put at 3.3 of 10 with a confidence of 35 of 100, because read from one part only, the share count over the years, which ranks in the bottom 33% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income. A filing that carries the missing parts replaces this estimate with the filed reading.

● Present

What are they doing right now?

3.1/1035% of the headline grade · 3 of 3 filed

Financial health

as filed
1.7/10

Is it financially healthy right now?

Leverage 197%: owes 197¢ per asset dollar.

weight 45% of this tense · 17th percentile among 473 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-12-31, Clene Inc.'s shareholders' equity was below zero, so the profit on it is not read, and gross profitability: its products earned about 1 cents per dollar of everything the company owns (revenue less the cost of revenue). Leverage: it owed about 197 cents per dollar of assets, and net share issuance: its share count grew 41.8% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetsbottom 3% of its family
  • gross profit against assetsbottom 13% of its family
  • the share count against the year beforebottom 35% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
1.3/10

How strong is its position in its industry?

bottom 13% of 315 in its family; net margin -13086.5%.

weight 22% of this tense · 13th percentile among 315 sector filers · read for its customers

From the record

Clene Inc.'s standing among 315 graded names in its industry family: revenue of $200 thousand in fiscal 2025 ranks in the bottom 10% by size; a net margin of -13086.5% ranks in the bottom 10%; revenue growth of -24.9% a year over the last 3 filed years ranks in the bottom 19% (its annual reports).

What it rests on

  • revenue against the family$200,000bottom 10% of its family
  • net margin-13086.5%bottom 10% of its family
  • three-year revenue growth-24.9%bottom 19% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
6.3/10

What are the people in charge doing?

top 37% of 315 in its family for leadership; chief executive since 2021.

weight 33% of this tense · 63rd percentile among 315 sector filers · read for its shareholders

From the record

Clene Inc.'s leadership, from its insiders' filings and its current reports: the chief executive on the record is Etherington, Robert Dee (President & CEO, as filed), filing under that title since 2021-01-04, 5.9 years (top 42% of its family); the 12 officers and directors filing in the last fifteen months have been on the record a median of 5.9 years (top 46%); 3 officer or director changes were reported on Form 8-K since 2023-11-13, against the 12 people in charge now (top 23%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge3 in three years among 12 peopletop 23% of its family
  • the median years the people in charge have filed5.9 yearstop 46% of its family
  • the chief executive's years on the record5.9 yearstop 42% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

2.7/1040% of the headline grade · 3 of 3 filed

Room to expand

as filed
4.1/10

How much room does it have to grow?

bottom 41% of 273 in its family for room to expand.

weight 33% of this tense · 41st percentile among 273 sector filers · read for itself

From the record

Clene Inc.'s room to grow, from the newest filed statements (fiscal 2025): cash of $5 million against debt of $18 million leaves -69.2% of its assets as net cash, bottom 1% of its family; cash from operations less capital spending is -9292.5% of revenue (bottom 8%); a gross margin of 78.5% (top 36%); research spending of 7005.5% of revenue (top 8%) (its annual report).

What it rests on

  • cash less debt against assets-69.2%bottom 1% of its family
  • cash from operations less capital spending against revenue-9292.5%bottom 8% of its family
  • gross margin78.5%top 36% of its family
  • research spending against revenue7005.5%top 8% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
1.5/10

What could actually drive growth from here?

bottom 15% of 306 in its family for growth drivers.

weight 45% of this tense · 15th percentile among 306 sector filers · read for its customers

From the record

Clene Inc.'s growth drivers, from the filed years to fiscal 2025: revenue grew -24.9% a year over the last three filed years against -0.6% over all 6, slowing (bottom 23% of its family); the newest year grew -41.5% (bottom 19%); research spending grew -24% a year (bottom 17%); capital spending grew -80.4% a year (bottom 2%) (its annual reports). Clene Inc. reported 2 product lines in fiscal 2025: Product at $119 thousand (60%), Royalty at $81 thousand (41%); 0 of 2 grew against the year before (its annual report).

What it rests on

  • three-year growth against the whole span-24.3 points a yearbottom 23% of its family
  • the newest year's revenue growth-41.5%bottom 19% of its family
  • three-year growth of research spending-24.0%bottom 17% of its family
  • three-year growth of capital spending-80.4%bottom 2% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
3.1/10

Did its newest year beat what its own record pointed to?

bottom 31% of 233 in its family for expectations against reality.

weight 22% of this tense · 31st percentile among 233 sector filers · read for its shareholders

From the record

Clene Inc.'s newest year against its own record: revenue of $200 thousand in fiscal 2025 came in 31.2% below the $291 thousand its prior three years' pace pointed to (bottom 25% of its family); net income of $26 million against a prior three-year average of $40 million (top 40%); a net margin of a loss larger than its revenue against losses larger than its revenue before (bottom 8%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace-31.2%bottom 25% of its family
  • net income against the prior three years' average+34%top 40% of its family
  • net margin against its prior averagedown more than 100 pointsbottom 8% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton CLNN · research, not advice