Patents
US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026
48 patents granted to the 2 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to Precision BioSciences, Inc.’s names, not what it holds today.
Patents granted
48
48 utility, 1976 to Dec 31, 2025
Granted in 2025
3
Against 3 in 2024 and 5 in 2023
Applications published
138
20 of them in 2025
Names they are printed under
2
its own name
By yearGrantedApplications published
'11'12'13'14'15'16'17'18'19'20'21'22'23'24'25
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Biotechnology17
Pharmaceuticals4
Medical technology1
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name2 counted
Precision Biosciences, Inc. its own name
US, as the owner printed on each patent
48 granted
124 publishedPrecision BioSciences, Inc. its own name
named as the applicant on its applications, in US
0 granted
14 published
Newest grantseach row opens the USPTO’s own copy
| Granted | Patent | Title | Field | Owner as printed |
|---|
| Oct 21, 2025 | 12,448,613 | Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene | Biotechnology | Precision Biosciences, Inc. |
| Sep 9, 2025 | 12,410,418 | Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome | Biotechnology | Precision Biosciences, Inc. |
| Jul 8, 2025 | 12,351,839 | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences | Biotechnology | Precision Biosciences, Inc. |
| Jun 11, 2024 | 12,006,522 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Biotechnology | Precision Biosciences, Inc. |
| May 28, 2024 | 11,993,793 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Biotechnology | Precision Biosciences, Inc. |
| Jan 9, 2024 | 11,866,747 | Engineered meganucleases that target human mitochondrial genomes | Pharmaceuticals | Precision Biosciences, Inc. |
| Dec 26, 2023 | 11,851,680 | Genetically-modified immune cells comprising a microRNA-adapted shRNA (shRNAmiR) | Biotechnology | Precision Biosciences, Inc. |
| Oct 17, 2023 | 11,788,077 | Polynucleotides encoding optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome | Biotechnology | Precision Biosciences, Inc. |
| Oct 17, 2023 | 11,786,554 | Optimized engineered nucleases having specificity for the human T cell receptor alpha constant region gene | Medical technology | Precision Biosciences, Inc. |
| Sep 12, 2023 | 11,753,630 | Polynucleotides encoding engineered meganucleases having specificity for recognition sequences in the dystrophin gene | Biotechnology | Precision Biosciences, Inc. |
Newest applications publishedan application is a clue, never a plan
| Published | Application | Title | Field | Owner as printed |
|---|
| Dec 18, 2025 | 2025/0382641 | POLYPEPTIDE LINKERS FOR USE IN ENGINEERED MEGANUCLEASES | Biotechnology | Precision Biosciences, Inc. |
| Nov 13, 2025 | 2025/0346877 | ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME | Pharmaceuticals | Precision Biosciences, Inc. |
| Oct 30, 2025 | 2025/0333468 | OPTIMIZED ENGINEERED NUCLEASES HAVING SPECIFICITY FOR THE HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE | Medical technology | Precision Biosciences, Inc. |
| Oct 9, 2025 | 2025/0313816 | GENETICALLY-MODIFIED CELLS COMPRISING A MODIFIED TRANSFERRIN GENE | Biotechnology | Precision Biosciences, Inc. |
| Oct 2, 2025 | 2025/0304949 | GENETIC MODIFICATION OF THE HYDROXYACID OXIDASE 1 GENE FOR TREATMENT OF PRIMARY HYPEROXALURIA | Biotechnology | Precision Biosciences, Inc. |
| Jul 17, 2025 | 2025/0228973 | GENE EDITING METHODS FOR TREATING ALPHA-1 ANTITRYPSIN (AAT) DEFICIENCY | Pharmaceuticals | Precision BioSciences, Inc. |
| May 29, 2025 | 2025/0171757 | OPTIMIZED ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME | Biotechnology | Precision Biosciences, Inc. |
| May 15, 2025 | 2025/0154486 | ENGINEERED MEGANUCLEASES SPECIFIC FOR RECOGNITION SEQUENCES IN THE HEPATITIS B VIRUS GENOME | Pharmaceuticals | Precision Biosciences, Inc. |
| May 15, 2025 | 2025/0154485 | RATIONALLY-DESIGNED SINGLE-CHAIN MEGANUCLEASES WITH NON-PALINDROMIC RECOGNITION SEQUENCES | Biotechnology | Precision Biosciences, Inc. |
| May 15, 2025 | 2025/0154481 | ENGINEERED MEGANUCLEASES SPECIFIC FOR RECOGNITION SEQUENCES IN THE PCSK9 GENE | Biotechnology | Precision Biosciences, Inc. |
What it applied for, 2024 to 2025: Biotechnology 26 · Pharmaceuticals 13 · Medical technology 2.
A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.