Patents
US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026
8 patents granted to the 2 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to Fulcrum Therapeutics, Inc.’s names, not what it holds today.
Patents granted
8
8 utility, 1976 to Dec 31, 2025
Granted in 2025
none
Against 1 in 2024 and 2 in 2023
Applications published
19
3 of them in 2025
Names they are printed under
2
its own name
By yearGrantedApplications published
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Organic fine chemistry3
Pharmaceuticals3
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name2 counted
Fulcrum Therapeutics, Inc. its own name
named as the applicant on its applications, in US
0 granted
17 publishedFulcrum Therapeutics, Inc. its own name
US, as the owner printed on each patent
8 granted
2 published
Newest grantseach row opens the USPTO’s own copy
| Granted | Patent | Title | Field | Owner as printed |
|---|
| Oct 8, 2024 | 12,109,198 | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| Nov 21, 2023 | 11,819,554 | Compositions and methods for modulating FMR1 expression | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Feb 28, 2023 | 11,590,111 | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| Oct 25, 2022 | 11,479,770 | Use of p38 inhibitors to reduce expression of DUX4 | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Apr 5, 2022 | 11,291,659 | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Apr 13, 2021 | 10,973,805 | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| Jan 21, 2020 | 10,537,560 | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Jul 9, 2019 | 10,342,786 | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
Newest applications publishedan application is a clue, never a plan
| Published | Application | Title | Field | Owner as printed |
|---|
| Jul 10, 2025 | 2025/0223560 | NOX4 INHIBITOR COMPOSITIONS AND METHODS FOR REGENERATION OF DYSTROPHIC MUSCLE | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Jul 3, 2025 | 2025/0213543 | AN EMBRYONIC ECTODERM DEVELOPMENT INHIBITOR FOR THE TREATMENT OF SICKLE CELL DISEASE | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Jun 19, 2025 | 2025/0195480 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| Nov 7, 2024 | 2024/0368185 | MACROCYCLIC AZOLOPYRIDINES | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| Oct 17, 2024 | 2024/0342148 | METHODS OF TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY WITH LOSMAPIMOD | Medical technology | Fulcrum Therapeutics, Inc. |
| Jul 18, 2024 | 2024/0238296 | METHODS OF REGULATING BCL11A EXPRESSION AND TREATMENT OF BCL11A-MEDIATED DISORDERS | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Jun 20, 2024 | 2024/0199645 | POLYMORPHIC FORMS OF (S)-12-FLUORO-4-(1-METHYL-1H-PYRAZOL-5-YL)-7A,8,13,14-TETRAHYDRO-7H-[1,2,4]TRIAZOLO[4',3':1,6]PYRIDO[3,2-B]BENZOFURO[4,3-FG][1,4]OXAZONINE | Organic fine chemistry | Fulcrum Therapeutics, Inc. |
| May 2, 2024 | 2024/0139163 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Organic fine chemistry | Fulcrum Therapeutics, Inc. · patent 12,109,198 granted from it |
| Aug 17, 2023 | 2023/0257743 | USE OF P38 INHIBITORS TO REDUCE EXPRESSION OF DUX4 | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
| Sep 8, 2022 | 2022/0282254 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | Pharmaceuticals | Fulcrum Therapeutics, Inc. |
What it applied for, 2024 to 2025: Organic fine chemistry 4 · Pharmaceuticals 3 · Medical technology 1.
A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.