Patents
US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026
60 patents granted to the 2 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to GRAIL, Inc.’s names, not what it holds today.
Patents granted
60
60 utility, 1976 to Dec 31, 2025
Granted in 2025
14
Against 13 in 2024 and 14 in 2023
Applications published
187
16 of them in 2025
Names they are printed under
2
its own name
By yearGrantedApplications published
'14'17'18'19'20'21'22'23'24'25
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Computer technology32
Biotechnology21
Organic fine chemistry1
Medical technology1
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name2 counted
GRAIL, Inc. its own name
named as the applicant on its applications, in US
0 granted
164 publishedGRAIL, Inc. its own name
US, as the owner printed on each patent
60 granted
23 published
Newest grantseach row opens the USPTO’s own copy
| Granted | Patent | Title | Field | Owner as printed |
|---|
| Dec 30, 2025 | 12,509,726 | Methods of preparing dual-indexed DNA libraries for bisulfite conversion sequencing | Biotechnology | GRAIL, Inc. |
| Dec 16, 2025 | 12,499,972 | Identifying false positive variants using a significance model | Computer technology | GRAIL, Inc. |
| Dec 16, 2025 | 12,497,662 | Systems and methods for tumor fraction estimation from small variants | Computer technology | GRAIL, Inc. |
| Nov 4, 2025 | 12,460,269 | Methods for analyzing viral nucleic acid | Biotechnology | GRAIL, Inc. |
| Oct 7, 2025 | 12,435,375 | Methylation markers and targeted methylation probe panel | Biotechnology | GRAIL, Inc. |
| Sep 9, 2025 | 12,410,482 | Methylation markers and targeted methylation probe panel | Computer technology | GRAIL, Inc. |
| Aug 12, 2025 | 12,385,037 | Enrichment of short nucleic acid fragments in sequencing library preparation | Biotechnology | GRAIL, Inc. |
| Aug 5, 2025 | 12,380,964 | Convolutional neural network systems and methods for data classification | Computer technology | GRAIL, Inc. |
| Apr 1, 2025 | 12,264,364 | Methods of preparing dual-indexed DNA libraries for bisulfite conversion sequencing | Biotechnology | GRAIL, Inc. |
| Mar 11, 2025 | 12,247,259 | Using nucleic acid size range for noninvasive cancer detection | Computer technology | GRAIL, Inc. |
Newest applications publishedan application is a clue, never a plan
| Published | Application | Title | Field | Owner as printed |
|---|
| Nov 13, 2025 | 2025/0349431 | Multi-Assay Prediction Model for Cancer Detection | Computer technology | GRAIL, Inc. |
| Nov 13, 2025 | 2025/0346961 | METHODS AND SYSTEMS FOR TUMOR DETECTION | Computer technology | GRAIL, Inc. |
| Nov 6, 2025 | 2025/0342964 | Cancer Classification with Tissue of Origin Thresholding | Computer technology | GRAIL, Inc. |
| Sep 25, 2025 | 2025/0297325 | SOURCE OF ORIGIN DECONVOLUTION BASED ON METHYLATION FRAGMENTS IN CELL-FREE DNA SAMPLES | Computer technology | GRAIL, Inc. |
| Sep 18, 2025 | 2025/0292864 | Detecting Cross Contamination in Sequencing Data | Computer technology | GRAIL, Inc. |
| Sep 11, 2025 | 2025/0284956 | SYSTEMS AND METHODS FOR USING A CONVOLUTIONAL NEURAL NETWORK TO DETECT CONTAMINATION | Computer technology | GRAIL, Inc. |
| Sep 11, 2025 | 2025/0283161 | PREPARATION OF NUCLEIC ACID SAMPLES FOR SEQUENCING | Biotechnology | GRAIL, Inc. |
| Aug 14, 2025 | 2025/0258070 | LIQUID PROCESSING SYSTEM AND RELATED METHODS | Measurement | GRAIL, Inc. |
| Jun 19, 2025 | 2025/0197935 | Methods of Preparing Dual-Indexed DNA Libraries for Bisulfite Conversion Sequencing | Biotechnology | GRAIL, Inc. · patent 12,509,726 granted from it |
| Apr 24, 2025 | 2025/0132055 | PARALLEL CANCER SOURCE OF ORIGIN CLASSIFICATION FOR ORGAN TYPE AND TUMOR BIOLOGY TYPE | Computer technology | GRAIL, Inc. |
What it applied for, 2024 to 2025: Computer technology 34 · Biotechnology 11 · Medical technology 4 · Analysis of biological materials 1 · Measurement 1.
A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.