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Ligand Pharmaceuticals Incorporated (LGND)

Nasdaq: LGND · Pharmaceutical Preparations · San Diego, CA · filing with the SEC since 1994
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Grade6.3
◀ Past 5.7● Present 6.9▶ Future 6.0
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Patents

US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026

761 patents granted to the 15 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to Ligand Pharmaceuticals Incorporated’s names, not what it holds today.

Patents granted
761
760 utility, 1 reissue, 1976 to Dec 31, 2025
Granted in 2025
8
Against 3 in 2024 and 5 in 2023
Applications published
391
3 of them in 2025
Names they are printed under
15
a subsidiary, its own name
By yearGrantedApplications published
'11'12'13'14'15'16'17'18'19'20'21'22'23'24'25
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Pharmaceuticals23
Organic fine chemistry8
Biotechnology3
Macromolecular chemistry, polymers1
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name15 counted
Neurogen Corporation a subsidiary
US, as the owner printed on each patent
312 granted
108 published
Ligand Pharmaceuticals Incorporated its own name
US, as the owner printed on each patent
177 granted
39 published
PHARMACOPEIA, LLC a subsidiary
US, as the owner printed on each patent
102 granted
35 published
Metabasis Therapeutics, Inc. a subsidiary
US, as the owner printed on each patent
64 granted
24 published
CyDex Pharmaceuticals, Inc. a subsidiary
US, as the owner printed on each patent
51 granted
21 published
CyDex Pharmaceuticals, Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
42 published
Ligand Pharmaceuticals Incorporated its own name
named as the applicant on its applications, in US
0 granted
42 published
Pfenex Inc. a subsidiary
US, as the owner printed on each patent
30 granted
8 published
APEIRON BIOLOGICS AG a subsidiary
AT, as the owner printed on each patent
15 granted
15 published
Metabasis Therapeutics, Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
18 published
Neurogen Corporation, A Corporation of the State of Delaware a subsidiary
US, as the owner printed on each patent
0 granted
16 published
Pfenex Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
15 published
Seragen, Inc. a subsidiary
US, as the owner printed on each patent
9 granted
0 published
APEIRON BIOLOGICS AG a subsidiary
named as the applicant on its applications, in AT
0 granted
7 published
Ligand UK Development Limited a subsidiary
GB, as the owner printed on each patent
1 granted
1 published
Newest grantseach row opens the USPTO’s own copy
GrantedPatentTitleFieldOwner as printed
Dec 23, 202512,503,428Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structuresOrganic fine chemistryLigand Pharmaceuticals Incorporated
Oct 14, 202512,440,502Use of thyroid beta-agonistsPharmaceuticalsMetabasis Therapeutics, Inc.
Sep 2, 202512,403,087Topical antiviral compositions, delivery systems, and methods of using the samePharmaceuticalsLigand Pharmaceuticals Incorporated
Aug 19, 202512,390,506Compositions containing silymarin and sulfoalkyl ether cyclodextrin and methods of using the samePharmaceuticalsCyDex Pharmaceuticals, Inc.
Jul 29, 202512,370,352Nasal and ophthalmic delivery of aqueous corticosteroid solutionsPharmaceuticalsCyDex Pharmaceuticals, Inc.
Jun 3, 202512,319,651Crystalline forms and methods of producing crystalline forms of a compoundOrganic fine chemistryLigand Pharmaceuticals Incorporated
Mar 11, 202512,246,014Azetidine derivativesPharmaceuticalsLigand UK Development Limited
Jan 28, 202512,208,071Glucagon receptor antagonistsPharmaceuticalsLigand Pharmaceuticals Incorporated
Apr 30, 202411,970,482Acetal compounds and therapeutic uses thereofPharmaceuticalsLigand Pharmaceuticals Incorporated
Apr 9, 202411,951,114Use of thyroid beta-agonistsPharmaceuticalsMetabasis Therapeutics, Inc.
Newest applications publishedan application is a clue, never a plan
PublishedApplicationTitleFieldOwner as printed
Nov 27, 20252025/0360211POPULATION OF TRANSFECTED IMMUNE CELLS AND METHOD FOR THEIR PRODUCTIONBiotechnologyAPEIRON BIOLOGICS AG
Jun 12, 20252025/0188111CYCLIC PHOSPHORAMIDATE COMPOUNDSPharmaceuticalsLigand Pharmaceuticals Incorporated
Jan 2, 20252025/0000880USE OF THYROID BETA-AGONISTSPharmaceuticalsMetabasis Therapeutics, Inc. · patent 12,440,502 granted from it
Sep 5, 20242024/0294565UNNATURAL CONFIGURATION NUCLEOTIDE PRODRUG COMPOUNDSPharmaceuticalsLigand Pharmaceuticals Incorporated
May 16, 20242024/0158530PREPARATIONS AND METHODS FOR TREATING A GD2 POSITIVE CANCERPharmaceuticalsAPEIRON BIOLOGICS AG
May 16, 20242024/0156766INJECTABLE MELPHALAN COMPOSITIONS COMPRISING A CYCLODEXTRIN DERIVATIVE AND METHODS OF MAKING AND USING THE SAMEPharmaceuticalsCyDex Pharmaceuticals, Inc.
May 2, 20242024/0139137Injectable Nitrogen Mustard Compositions Comprising a Cyclodextrin Derivative and Methods of Making and Using the SamePharmaceuticalsCyDex Pharmaceuticals, Inc.
Mar 21, 20242024/0093173METHODS FOR TREATMENT OF VIRUSPharmaceuticalsAPEIRON BIOLOGICS AG
Dec 7, 20232023/0391807ANTIVIRAL PRODRUG COMPOUNDSOrganic fine chemistryLigand Pharmaceuticals Incorporated
Nov 9, 20232023/0357451ALKYLATED CYCLODEXTRIN COMPOSITIONS AND PROCESSES FOR PREPARING AND USING THE SAMEChemical engineeringCyDex Pharmaceuticals, Inc.
What it applied for, 2024 to 2025: Pharmaceuticals 7 · Biotechnology 1.

A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.

SI Assistanton LGND · research, not advice