Company Analysis

Lexicon Pharmaceuticals, Inc. (LXRX)

Nasdaq: LXRX · Pharmaceutical Preparations · The Woodlands, TX · filing with the SEC since 2000
Grade5.2
◀ Past 3.7● Present 5.7▶ Future 6.2
1 est.

The grade of Lexicon Pharmaceuticals, Inc.

Nine metrics read from its own filings, by tense
Headline grade
5.2/10
◀ Past3.730% of the headline
● Present5.740% of the headline
▶ Future6.230% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

Of the nine metrics, 8 read as filed from the record and 1 is an SI estimate, each with its reasoning, its confidence and what would change it on its card.

◀ Past

What did they actually do?

3.7/1030% of the headline grade · 2 of 3 filed, 1 estimated

Surviving crises

as filed
3.5/10

Has it survived what it has been through?

1 warning event since 2017; the latest 2025-01-07.

weight 33% of this tense · 35th percentile among 497 sector filers · read for itself

From the record

Lexicon Pharmaceuticals, Inc.'s filings since 2017 show 1 warning event: a notice about its exchange listing (8-K item 3.01, the latest 2025-01-07) (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
3.6/10

What has it actually done, year after year?

-5% a year over 10 filed years; profitable in 1 of 10.

weight 45% of this tense · 36th percentile among 323 sector filers · read for its customers

From the record

Lexicon Pharmaceuticals, Inc.'s 10 filed years say what it did: revenue went from $79 million in fiscal 2016 to $50 million in fiscal 2025, down 5% a year; it rose in 5 of 9 years; the deepest fall was 100% from fiscal 2019 to fiscal 2022; net income was positive in 1 of 10 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span-5.0%bottom 22% of its family
  • the share of years revenue rosebottom 44% of its family
  • the share of filed years with a profittop 42% of its family
  • the deepest fall from a revenue peak100.0%bottom 19% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

SI estimate
4.3/10

How has it treated the people who own it?

SI estimate 4.3/10, confidence 35 of 100 (one part).

weight 22% of this tense · 43rd percentile among 464 sector filers · read for its shareholders

SI estimate Inferred, not read as filed

Why it is an estimate
Read from one part only, the share count over the years, which ranks in the bottom 43% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
What the record cannot read
Fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
How it was reasoned
one part: the share count over the years, the one part on file, ranked among 464 in its family.
Confidence
35 of 100
What would change it
A filing that carries the missing parts replaces this estimate with the filed reading.

From the record

SI estimate, not a filed reading: Lexicon Pharmaceuticals, Inc.'s shareholder treatment is put at 4.3 of 10 with a confidence of 35 of 100, because read from one part only, the share count over the years, which ranks in the bottom 43% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income. A filing that carries the missing parts replaces this estimate with the filed reading.

● Present

What are they doing right now?

5.7/1040% of the headline grade · 3 of 3 filed

Financial health

as filed
5.2/10

Is it financially healthy right now?

ROE -47%: lost 47¢ per shareholder dollar. Leverage 42%: owes 42¢ per asset dollar.

weight 45% of this tense · 52nd percentile among 473 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-12-31, Lexicon Pharmaceuticals, Inc. lost about 47 cents for every dollar of shareholders' money, and gross profitability: its products earned about 27 cents per dollar of everything the company owns (revenue less the cost of revenue). Leverage: it owed about 42 cents per dollar of assets, and net share issuance: its share count grew 13.4% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetsbottom 42% of its family
  • return on equitytop 46% of its family
  • gross profit against assetstop 47% of its family
  • the share count against the year beforetop 42% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
6.9/10

How strong is its position in its industry?

top 31% of 315 in its family; net margin -101.1%.

weight 33% of this tense · 69th percentile among 315 sector filers · read for its customers

From the record

Lexicon Pharmaceuticals, Inc.'s standing among 315 graded names in its industry family: revenue of $50 million in fiscal 2025 ranks in the top 44% by size; a net margin of -101.1% ranks in the top 46%; revenue growth of 609.9% a year over the last 3 filed years ranks in the top 2% (its annual reports).

What it rests on

  • revenue against the family$49.8Mtop 44% of its family
  • net margin-101.1%top 46% of its family
  • three-year revenue growth609.9%top 2% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
4.9/10

What are the people in charge doing?

bottom 49% of 315 in its family for leadership; chief executive since 2024.

weight 22% of this tense · 49th percentile among 315 sector filers · read for its shareholders

From the record

Lexicon Pharmaceuticals, Inc.'s leadership, from its insiders' filings and its current reports: the chief executive on the record is Exton, Michael (Chief Executive Officer, as filed), filing under that title since 2024-07-08, 2.3 years (bottom 26% of its family); the 18 officers and directors filing in the last fifteen months have been on the record a median of 5.5 years (bottom 49%); 5 officer or director changes were reported on Form 8-K since 2023-11-13, against the 18 people in charge now (top 27%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge5 in three years among 18 peopletop 27% of its family
  • the median years the people in charge have filed5.5 yearsbottom 49% of its family
  • the chief executive's years on the record2.3 yearsbottom 26% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

6.2/1030% of the headline grade · 3 of 3 filed

Room to expand

as filed
5.2/10

How much room does it have to grow?

top 48% of 273 in its family for room to expand.

weight 45% of this tense · 52nd percentile among 273 sector filers · read for itself

From the record

Lexicon Pharmaceuticals, Inc.'s room to grow, from the newest filed statements (fiscal 2025): cash of $34 million against debt of $49 million leaves -8.2% of its assets as net cash, bottom 11% of its family; cash from operations less capital spending is -136.2% of revenue (bottom 47%); a gross margin of 99.4% (top 2%); research spending of 122.7% of revenue (top 48%) (its annual report).

What it rests on

  • cash less debt against assets-8.2%bottom 11% of its family
  • cash from operations less capital spending against revenue-136.2%bottom 47% of its family
  • gross margin99.4%top 2% of its family
  • research spending against revenue122.7%top 48% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
7.7/10

What could actually drive growth from here?

top 23% of 306 in its family for growth drivers.

weight 33% of this tense · 77th percentile among 306 sector filers · read for its customers

From the record

Lexicon Pharmaceuticals, Inc.'s growth drivers, from the filed years to fiscal 2025: revenue grew 609.9% a year over the last three filed years against -5% over all 10, speeding up (top 1% of its family); the newest year grew 60.3% (top 22%); research spending grew 5% a year (top 46%) (its annual reports). Lexicon Pharmaceuticals, Inc. reported 2 product lines in fiscal 2025: License at $45 million (91%), Product at $5 million (9%); 1 of 2 grew against the year before (its annual report).

What it rests on

  • three-year growth against the whole span+615.0 points a yeartop 1% of its family
  • the newest year's revenue growth60.3%top 22% of its family
  • three-year growth of research spending5.0%top 46% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
6.0/10

Did its newest year beat what its own record pointed to?

top 40% of 233 in its family for expectations against reality.

weight 22% of this tense · 60th percentile among 233 sector filers · read for its shareholders

From the record

Lexicon Pharmaceuticals, Inc.'s newest year against its own record: revenue of $50 million in fiscal 2025 came in 89.3% below the $464 million its prior three years' pace pointed to (bottom 7% of its family); net income of $50 million against a prior three-year average of $160 million (top 24%); a net margin of a loss larger than its revenue against losses larger than its revenue before (top 3%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace-89.3%bottom 7% of its family
  • net income against the prior three years' average+69%top 24% of its family
  • net margin against its prior averageup more than 100 pointstop 3% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton LXRX · research, not advice