Company Analysis

uniQure N.V. (QURE)

Nasdaq: QURE · Pharmaceutical Preparations · Amsterdam · filing with the SEC since 2013
Grade4.1
◀ Past 5.1● Present 4.1▶ Future 3.5
1 est.

The grade of uniQure N.V.

Nine metrics read from its own filings, by tense
Headline grade
4.1/10
◀ Past5.125% of the headline
● Present4.135% of the headline
▶ Future3.540% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

Of the nine metrics, 8 read as filed from the record and 1 is an SI estimate, each with its reasoning, its confidence and what would change it on its card.

◀ Past

What did they actually do?

5.1/1025% of the headline grade · 2 of 3 filed, 1 estimated

Surviving crises

as filed
6.2/10

Has it survived what it has been through?

1 warning event since 2017; the latest 2019-04-29.

weight 22% of this tense · 62nd percentile among 497 sector filers · read for itself

From the record

uniQure N.V.'s filings since 2017 show 1 warning event: an auditor change (8-K item 4.01, the latest 2019-04-29) (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
3.1/10

What has it actually done, year after year?

-4.8% a year over 10 filed years; profitable in 1 of 10.

weight 45% of this tense · 31st percentile among 323 sector filers · read for its customers

From the record

uniQure N.V.'s 10 filed years say what it did: revenue went from $25 million in fiscal 2016 to $16 million in fiscal 2025, down 4.8% a year; it rose in 3 of 9 years; the deepest fall was 97% from fiscal 2021 to fiscal 2023; net income was positive in 1 of 10 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span-4.8%bottom 23% of its family
  • the share of years revenue rosebottom 17% of its family
  • the share of filed years with a profittop 42% of its family
  • the deepest fall from a revenue peak97.0%bottom 26% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

SI estimate
7.0/10

How has it treated the people who own it?

SI estimate 7.0/10, confidence 35 of 100 (one part).

weight 33% of this tense · 70th percentile among 464 sector filers · read for its shareholders

SI estimate Inferred, not read as filed

Why it is an estimate
Read from one part only, the share count over the years, which ranks in the top 30% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
What the record cannot read
Fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
How it was reasoned
one part: the share count over the years, the one part on file, ranked among 464 in its family.
Confidence
35 of 100
What would change it
A filing that carries the missing parts replaces this estimate with the filed reading.

From the record

SI estimate, not a filed reading: uniQure N.V.'s shareholder treatment is put at 7.0 of 10 with a confidence of 35 of 100, because read from one part only, the share count over the years, which ranks in the top 30% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income. A filing that carries the missing parts replaces this estimate with the filed reading.

● Present

What are they doing right now?

4.1/1035% of the headline grade · 3 of 3 filed

Financial health

as filed
3.0/10

Is it financially healthy right now?

ROE -100%: lost 100¢ per shareholder dollar. Leverage 76%: owes 76¢ per asset dollar.

weight 45% of this tense · 30th percentile among 473 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-12-31, uniQure N.V. lost about 100 cents for every dollar of shareholders' money, and gross profitability: its products earned about 2 cents per dollar of everything the company owns (revenue less the cost of revenue). Leverage: it owed about 76 cents per dollar of assets, and net share issuance: its share count grew 18.2% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetsbottom 19% of its family
  • return on equitybottom 32% of its family
  • gross profit against assetsbottom 16% of its family
  • the share count against the year beforetop 48% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
2.8/10

How strong is its position in its industry?

bottom 28% of 315 in its family; net margin -1236%.

weight 22% of this tense · 28th percentile among 315 sector filers · read for its customers

From the record

uniQure N.V.'s standing among 315 graded names in its industry family: revenue of $16 million in fiscal 2025 ranks in the bottom 46% by size; a net margin of -1236% ranks in the bottom 27%; revenue growth of -46.7% a year over the last 3 filed years ranks in the bottom 10% (its annual reports).

What it rests on

  • revenue against the family$16.1Mbottom 46% of its family
  • net margin-1236.0%bottom 27% of its family
  • three-year revenue growth-46.7%bottom 10% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
6.7/10

What are the people in charge doing?

top 33% of 315 in its family for leadership; chief executive since 2017.

weight 33% of this tense · 67th percentile among 315 sector filers · read for its shareholders

From the record

uniQure N.V.'s leadership, from its insiders' filings and its current reports: the chief executive on the record is Kapusta, Matthew C (CEO, Managing Director, as filed), filing under that title since 2017-01-05, 9.9 years (top 17% of its family); the 12 officers and directors filing in the last fifteen months have been on the record a median of 8.4 years (top 18%); 7 officer or director changes were reported on Form 8-K since 2023-11-13, against the 12 people in charge now (bottom 35%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge7 in three years among 12 peoplebottom 35% of its family
  • the median years the people in charge have filed8.4 yearstop 18% of its family
  • the chief executive's years on the record9.9 yearstop 17% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

3.5/1040% of the headline grade · 3 of 3 filed

Room to expand

as filed
5.1/10

How much room does it have to grow?

top 49% of 273 in its family for room to expand.

weight 33% of this tense · 51st percentile among 273 sector filers · read for itself

From the record

uniQure N.V.'s room to grow, from the newest filed statements (fiscal 2025): cash of $80 million against debt of $50 million leaves 3.7% of its assets as net cash, bottom 18% of its family; cash from operations less capital spending is -1108.2% of revenue (bottom 23%); a gross margin of 89.5% (top 16%); research spending of 873.9% of revenue (top 22%) (its annual report).

What it rests on

  • cash less debt against assets3.7%bottom 18% of its family
  • cash from operations less capital spending against revenue-1108.2%bottom 23% of its family
  • gross margin89.5%top 16% of its family
  • research spending against revenue873.9%top 22% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
1.7/10

What could actually drive growth from here?

bottom 17% of 306 in its family for growth drivers.

weight 45% of this tense · 17th percentile among 306 sector filers · read for its customers

From the record

uniQure N.V.'s growth drivers, from the filed years to fiscal 2025: revenue grew -46.7% a year over the last three filed years against -4.8% over all 10, slowing (bottom 14% of its family); the newest year grew -40.7% (bottom 20%); research spending grew -10.7% a year (bottom 30%); capital spending grew -70.8% a year (bottom 5%) (its annual reports). uniQure N.V. reported 2 product lines in fiscal 2025: License at $16 million (99%), Collaborative Revenue at $164 thousand (1%); 1 of 2 grew against the year before (its annual report).

What it rests on

  • three-year growth against the whole span-41.9 points a yearbottom 14% of its family
  • the newest year's revenue growth-40.7%bottom 20% of its family
  • three-year growth of research spending-10.7%bottom 30% of its family
  • three-year growth of capital spending-70.8%bottom 5% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
4.6/10

Did its newest year beat what its own record pointed to?

bottom 46% of 233 in its family for expectations against reality.

weight 22% of this tense · 46th percentile among 233 sector filers · read for its shareholders

From the record

uniQure N.V.'s newest year against its own record: revenue of $16 million in fiscal 2025 came in 17.6% above the $14 million its prior three years' pace pointed to (top 28% of its family); net income of $199 million against a prior three-year average of $225 million (bottom 48%); a net margin of a loss larger than its revenue against losses larger than its revenue before (bottom 18%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace17.6%top 28% of its family
  • net income against the prior three years' average+12%bottom 48% of its family
  • net margin against its prior averagedown more than 100 pointsbottom 18% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton QURE · research, not advice