Spruce Biosciences, Inc. (SPRB)
Nasdaq: SPRB · Pharmaceutical Preparations · South San Francisco, CA · filing with the SEC since 2020
Who owns Spruce Biosciences, Inc.
As filed with the SECHolders of 5% or more
4
Orin Hirschman holds 9.1% of Common Stock, par value $0.0001 per share, as its SCHEDULE 13G filed Jul 27, 2026 says.
Directors and officers
12
report now, of 18 people on the record since 2020. Their holdings as a group are not read here.
Institutions as a whole
n/a
The record does not read the share held by managers that file Form 13F, so none is printed and no split of the rest is estimated. What it holds is the 4 named at left.
Holders of 5% or moreshare of the class, as filed
Orin Hirschman
SCHEDULE 13G · filed Jul 27, 2026 · Common Stock, par value $0.0001 per share
Blackrock, Inc.
SCHEDULE 13G · filed Jul 30, 2026 · Common Stock
Boone Peter David Mr
SCHEDULE 13G · filed Nov 24, 2025 · Common Stok, par value $0.0001
AWM Investment Company, Inc.
SCHEDULE 13G · filed Aug 14, 2026 · Common Stock, $0.0001 Par Value
Integrated Core Strategies (US) LLC
SCHEDULE 13G/A · filed Aug 4, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%, from 9.6% in Feb 24, 2026
OrbiMed Advisors LLC
SCHEDULE 13G · filed Aug 14, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%
Ikarian Capital, LLC
SCHEDULE 13G/A · filed May 7, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%, from 11.4% in Nov 7, 2025
The Carlyle Group Inc.
SCHEDULE 13D/A · filed Feb 18, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%
Alyeska Investment Group, L.P.
SCHEDULE 13G/A · filed May 15, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%, from 5.79% in Feb 17, 2026
John P. McKearn, Ph.D.
SCHEDULE 13D/A · filed Jan 10, 2025 · Common Stock, par value $0.001 per share · reported falling below 5%
Wellington Management Group LLP
SCHEDULE 13G/A · filed May 15, 2026 · Common Stock · reported falling below 5%, from 5.5% in Feb 10, 2026
HealthCap VIII, L.P.
SCHEDULE 13D/A · filed Oct 9, 2025 · Common Stock, par value $0.0001 per share · reported falling below 5%
ADAR1 Capital Management, LLC
SCHEDULE 13G/A · filed Aug 14, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%, from 5.4% in Feb 17, 2026
Kenneth Griffin
SCHEDULE 13G/A · filed Aug 14, 2026 · Common Stock, par value $0.0001 per share (the "Shares") · reported falling below 5%, from 5.1% in May 15, 2026
Squadron Master Fund LP
SCHEDULE 13G/A · filed May 15, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%, from 6.5% in Feb 17, 2026
ExodusPoint Capital Management, LP
SCHEDULE 13G · filed Apr 28, 2026 · Common Stock, par value $0.0001 per share · reported falling below 5%
Rock Springs Capital Management LP
SCHEDULE 13G/A · filed Aug 13, 2025 · Common Stock, par value $0.0001 per share · reported falling below 5%
Radoff Family Foundation
SCHEDULE 13G/A · filed Aug 13, 2025 · Common Stock, par value $0.0001 per share · reported falling below 5%
Rosalind Advisors, Inc.
SCHEDULE 13G/A · filed Feb 13, 2025 · Common shares · reported falling below 5%
What SPRB reports owning in othersstakes of 5% or more, and other ties
Spruce Biosciences, Inc. reports no stake in another company in the record.
Insider tradesForm 4
0sales
0purchases
0sales on a scheduled plan
0people selling
$0sold, in dollars
$0bought, in dollars
Open-market trades on Form 4 from Sep 30, 2025 to Sep 30, 2026. A scheduled plan is a selling program set in advance under SEC rule 10b5-1. The trades are listed as filed and do not feed the grade.
By calendar yearSoldBought
2023 runs to Sep 30, 2026. Dollars as filed, summed by the transaction date.
People who traded in the window1 of 28 on the roster
| Person | Role as filed | Sales | Sold | On a plan | Buys | Bought |
|---|---|---|---|---|---|---|
| Parkman Healthcare Partners LLC | 10% owner | 4 | $0 | 0 | 2 | $0 |