Spero Therapeutics, Inc. (SPRO)
Nasdaq: SPRO · Pharmaceutical Preparations · Cambridge, MA · filing with the SEC since 2017
Who runs Spero Therapeutics, Inc.
Officers and directors as they report to the SEC on Forms 3, 4 and 5, named as filedChief executive, as filed
Mahadevia Ankit
CEO and President. First filing Nov 2017, latest Sep 3, 2025, 14 filings in all.
Officers reporting now
4
of 12 people with a filing in the last fifteen months
Directors reporting now
8
25 people on the record since 2017
Officerssales are open-market, Nov 10, 2025 to Nov 10, 2026
| Name | Title as filed | First filing | Latest filing | Sales, 12 months |
|---|---|---|---|---|
| Rajavelu Esther | See Remarks | Nov 2023 | Nov 10, 2026 | 5 · $400,000 |
| Zack Debra | Chief Medical Officer | Aug 2026 | Aug 6, 2026 | none |
| Keutzer Timothy | Chief Operating Officer | Jan 2020 | Feb 9, 2026 | 4 · $100,000 |
| Mahadevia Ankit | CEO and President | Nov 2017 | Sep 3, 2025 | none |
Directorssales are open-market, Nov 10, 2025 to Nov 10, 2026
| Name | Role | First filing | Latest filing | Sales, 12 months |
|---|---|---|---|---|
| Ho William | director | Nov 2026 | Nov 10, 2026 | none |
| Deshpande Milind | director | Nov 2017 | Jun 25, 2026 | none |
| Jackson Scott Thomas | director | Apr 2020 | Jun 25, 2026 | none |
| Pottage John C Jr | director | Sep 2018 | Jun 25, 2026 | none |
| Smith Cynthia | director | Mar 2019 | Jun 25, 2026 | none |
| Thomas Frank E | director | Nov 2017 | Jun 25, 2026 | none |
| Tregoning Kathleen | director | Oct 2021 | Jun 25, 2026 | none |
| Vink Patrick V.J.J. | director | Nov 2017 | Jun 25, 2026 | none |
Earlier names on the record23, newest filing first
Shukla Sath · officer · last filing Feb 2025Hamed Kamal · officer · last filing Feb 2024Joseph Tamara L · officer · last filing Feb 2024Dipalma Stephen J. · officer · last filing Jul 2023Glaxosmithkline PLC · 10% owner · last filing Nov 2022Aquilo Capital Management, LLC · 10% owner · last filing Sep 2022Aquilo Capital, L.P. · 10% owner · last filing Sep 2022Larkin Cristina · officer · last filing Feb 2022Melnick David A. · officer · last filing Feb 2022Formela Jean Francois · director · last filing Aug 2021Sendek Joel · officer · last filing Jan 2019Parr Thomas R Jr · officer · last filing Jan 2019Breum Casper · director · last filing Jun 2018Southwell David P · director · last filing Jun 2018Goyal Vikas · director · last filing Nov 2017Halse Reza · director · last filing Nov 2017Alphabet Inc. · 10% owner · last filing Nov 2017Atlas Venture Associates Ix, L.P. · 10% owner · last filing Nov 2017Atlas Venture Associates Ix, LLC · 10% owner · last filing Nov 2017Atlas Venture Fund Ix, L.P. · 10% owner · last filing Nov 2017Gv 2015 Gp, L.L.C. · 10% owner · last filing Nov 2017Gv 2015, L.P. · 10% owner · last filing Nov 2017Lundbeckfond Invest A/s · 10% owner · last filing Nov 2017
A person is listed as reporting now after a filing in the last fifteen months. The record shows when someone last filed; it does not say why they stopped. Each name links to the filings on sec.gov.