Company Analysis

Stoke Therapeutics, Inc. (STOK)

Nasdaq: STOK · Pharmaceutical Preparations · Bedford, MA · filing with the SEC since 2014
Grade6.3
◀ Past 5.4● Present 6.9▶ Future 6.6
1 est.

The grade of Stoke Therapeutics, Inc.

Nine metrics read from its own filings, by tense
Headline grade
6.3/10
◀ Past5.430% of the headline
● Present6.940% of the headline
▶ Future6.630% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

Of the nine metrics, 8 read as filed from the record and 1 is an SI estimate, each with its reasoning, its confidence and what would change it on its card.

◀ Past

What did they actually do?

5.4/1030% of the headline grade · 2 of 3 filed, 1 estimated

Surviving crises

as filed
4.1/10

Has it survived what it has been through?

2 warning events since 2017; the latest 2026-03-27.

weight 33% of this tense · 41st percentile among 497 sector filers · read for itself

From the record

Stoke Therapeutics, Inc.'s filings since 2017 show 2 warning events of 2 kinds: a notice about its exchange listing (8-K item 3.01, the latest 2022-02-17); an auditor change (8-K item 4.01, the latest 2026-03-27) (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
6.1/10

What has it actually done, year after year?

+145.8% a year over 4 filed years; profitable in 0 of 4.

weight 45% of this tense · 61st percentile among 323 sector filers · read for its customers

From the record

Stoke Therapeutics, Inc.'s 4 filed years say what it did: revenue went from $12 million in fiscal 2022 to $184 million in fiscal 2025, up 145.8% a year; it rose in 2 of 3 years; the deepest fall was 29% from fiscal 2022 to fiscal 2023; net income was positive in 0 of 4 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span145.8%top 5% of its family
  • the share of years revenue rosetop 41% of its family
  • the share of filed years with a profitbottom 27% of its family
  • the deepest fall from a revenue peak29.2%top 36% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

SI estimate
5.6/10

How has it treated the people who own it?

SI estimate 5.6/10, confidence 35 of 100 (one part).

weight 22% of this tense · 56th percentile among 464 sector filers · read for its shareholders

SI estimate Inferred, not read as filed

Why it is an estimate
Read from one part only, the share count over the years, which ranks in the top 44% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
What the record cannot read
Fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
How it was reasoned
one part: the share count over the years, the one part on file, ranked among 464 in its family.
Confidence
35 of 100
What would change it
A filing that carries the missing parts replaces this estimate with the filed reading.

From the record

SI estimate, not a filed reading: Stoke Therapeutics, Inc.'s shareholder treatment is put at 5.6 of 10 with a confidence of 35 of 100, because read from one part only, the share count over the years, which ranks in the top 44% of 464 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income. A filing that carries the missing parts replaces this estimate with the filed reading.

● Present

What are they doing right now?

6.9/1040% of the headline grade · 3 of 3 filed

Financial health

as filed
7.3/10

Is it financially healthy right now?

ROE -2%: lost 2¢ per shareholder dollar. Leverage 16%: owes 16¢ per asset dollar.

weight 45% of this tense · 73rd percentile among 473 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-12-31, Stoke Therapeutics, Inc. lost about 2 cents for every dollar of shareholders' money. Leverage: it owed about 16 cents per dollar of assets, and net share issuance: its share count grew 9.6% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetstop 25% of its family
  • return on equitytop 17% of its family
  • the share count against the year beforetop 38% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
7.9/10

How strong is its position in its industry?

top 21% of 315 in its family; net margin -3.7%.

weight 33% of this tense · 79th percentile among 315 sector filers · read for its customers

From the record

Stoke Therapeutics, Inc.'s standing among 315 graded names in its industry family: revenue of $184 million in fiscal 2025 ranks in the top 29% by size; a net margin of -3.7% ranks in the top 26%; revenue growth of 145.8% a year over the last 3 filed years ranks in the top 9% (its annual reports).

What it rests on

  • revenue against the family$184Mtop 29% of its family
  • net margin-3.7%top 26% of its family
  • three-year revenue growth145.8%top 9% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
4.5/10

What are the people in charge doing?

bottom 45% of 315 in its family for leadership; chief executive since 2025.

weight 22% of this tense · 45th percentile among 315 sector filers · read for its shareholders

From the record

Stoke Therapeutics, Inc.'s leadership, from its insiders' filings and its current reports: the chief executive on the record is Smith, Ian F (Chief Executive Officer, as filed), filing under that title since 2025-03-20, 1.7 years (bottom 21% of its family); the 15 officers and directors filing in the last fifteen months have been on the record a median of 6.4 years (top 34%); 7 officer or director changes were reported on Form 8-K since 2023-11-13, against the 15 people in charge now (bottom 49%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge7 in three years among 15 peoplebottom 49% of its family
  • the median years the people in charge have filed6.4 yearstop 34% of its family
  • the chief executive's years on the record1.7 yearsbottom 21% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

6.6/1030% of the headline grade · 3 of 3 filed

Room to expand

as filed
5.9/10

How much room does it have to grow?

top 41% of 273 in its family for room to expand.

weight 45% of this tense · 59th percentile among 273 sector filers · read for itself

From the record

Stoke Therapeutics, Inc.'s room to grow, from the newest filed statements (fiscal 2025): cash of $84 million against no long-term debt tagged leaves 20.1% of its assets as net cash, bottom 40% of its family; cash from operations less capital spending is 24.4% of revenue (top 10%); research spending of 74.8% of revenue (bottom 46%) (its annual report).

What it rests on

  • cash less debt against assets20.1%bottom 40% of its family
  • cash from operations less capital spending against revenue24.4%top 10% of its family
  • research spending against revenue74.8%bottom 46% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
6.4/10

What could actually drive growth from here?

top 36% of 306 in its family for growth drivers.

weight 33% of this tense · 64th percentile among 306 sector filers · read for its customers

From the record

Stoke Therapeutics, Inc.'s growth drivers, from the filed years to fiscal 2025: revenue grew 145.8% a year over the last three filed years against 145.8% over all 4, speeding up (top 40% of its family); the newest year grew 405.1% (top 8%); research spending grew 21% a year (top 22%); capital spending grew -44.7% a year (bottom 25%) (its annual reports). Stoke Therapeutics, Inc. tags no split of its revenue by line in the annual report on file, so growth by line cannot be read here; research and capital spending are on the trend.

What it rests on

  • three-year growth against the whole span+0.0 points a yeartop 40% of its family
  • the newest year's revenue growth405.1%top 8% of its family
  • three-year growth of research spending21.0%top 22% of its family
  • three-year growth of capital spending-44.7%bottom 25% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
8.5/10

Did its newest year beat what its own record pointed to?

top 15% of 233 in its family for expectations against reality.

weight 22% of this tense · 85th percentile among 233 sector filers · read for its shareholders

From the record

Stoke Therapeutics, Inc.'s newest year against its own record: revenue of $184 million in fiscal 2025 came in 194% above the $63 million its prior three years' pace pointed to (top 12% of its family); net income of $7 million against a prior three-year average of $98 million (top 18%); a net margin of -3.7% against losses larger than its revenue before (top 16%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace194.0%top 12% of its family
  • net income against the prior three years' average+93%top 18% of its family
  • net margin against its prior averageup more than 100 pointstop 16% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton STOK · research, not advice