Company Analysis

Twist Bioscience Corporation (TWST)

Nasdaq: TWST · Biological Products, (No Diagnostic Substances) · South San Francisco, CA · filing with the SEC since 2013
Grade6.2
◀ Past 7.2● Present 7.6▶ Future 4.4
1 est.

The grade of Twist Bioscience Corporation

Nine metrics read from its own filings, by tense
Headline grade
6.2/10
◀ Past7.225% of the headline
● Present7.635% of the headline
▶ Future4.440% of the headline

All three tenses have at least two readings, so the archetype blend applies as printed.

Of the nine metrics, 8 read as filed from the record and 1 is an SI estimate, each with its reasoning, its confidence and what would change it on its card.

◀ Past

What did they actually do?

7.2/1025% of the headline grade · 2 of 3 filed, 1 estimated

Surviving crises

as filed
5.8/10

Has it survived what it has been through?

1 warning event since 2017; the latest 2022-03-09.

weight 22% of this tense · 58th percentile among 159 sector filers · read for itself

From the record

Twist Bioscience Corporation's filings since 2017 show 1 warning event: an auditor change (8-K item 4.01, the latest 2022-03-09) (its current reports).

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Track record

as filed
7.3/10

What has it actually done, year after year?

+55.9% a year over 9 filed years; profitable in 0 of 9.

weight 45% of this tense · 73rd percentile among 102 sector filers · read for its customers

From the record

Twist Bioscience Corporation's 9 filed years say what it did: revenue went from $11 million in fiscal 2017 to $377 million in fiscal 2025, up 55.9% a year; it rose in 8 of 8 years; it never fell from a peak; net income was positive in 0 of 9 of those years (its annual reports).

What it rests on

  • revenue growth over the filed span55.9%top 21% of its family
  • the share of years revenue rosetop 8% of its family
  • the share of filed years with a profitbottom 31% of its family
  • the deepest fall from a revenue peak0.0%top 9% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Shareholder treatment

SI estimate
8.0/10

How has it treated the people who own it?

SI estimate 8.0/10, confidence 35 of 100 (one part).

weight 33% of this tense · 80th percentile among 146 sector filers · read for its shareholders

SI estimate Inferred, not read as filed

Why it is an estimate
Read from one part only, the share count over the years, which ranks in the top 20% of 146 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
What the record cannot read
Fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income.
How it was reasoned
one part: the share count over the years, the one part on file, ranked among 146 in its family.
Confidence
35 of 100
What would change it
A filing that carries the missing parts replaces this estimate with the filed reading.

From the record

SI estimate, not a filed reading: Twist Bioscience Corporation's shareholder treatment is put at 8.0 of 10 with a confidence of 35 of 100, because read from one part only, the share count over the years, which ranks in the top 20% of 146 in its family; fewer than two of the parts can be read: the share count over the years, and the cash returned against a positive operating cash flow or net income. A filing that carries the missing parts replaces this estimate with the filed reading.

● Present

What are they doing right now?

7.6/1035% of the headline grade · 3 of 3 filed

Financial health

as filed
7.3/10

Is it financially healthy right now?

ROE -16%: lost 16¢ per shareholder dollar. Leverage 26%: owes 26¢ per asset dollar.

weight 45% of this tense · 73rd percentile among 147 sector filers · read for itself

From the record

Return on equity: in the fiscal year ended 2025-09-30, Twist Bioscience Corporation lost about 16 cents for every dollar of shareholders' money, and gross profitability: its products earned about 30 cents per dollar of everything the company owns (revenue less the cost of revenue). Leverage: it owed about 26 cents per dollar of assets, and net share issuance: its share count grew 3.1% over the year (the filed statements).

What it rests on

  • what it owes per dollar of assetstop 34% of its family
  • return on equitytop 20% of its family
  • gross profit against assetstop 35% of its family
  • the share count against the year beforetop 20% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Industry position

as filed
7.4/10

How strong is its position in its industry?

top 26% of 102 in its family; net margin -20.6%.

weight 22% of this tense · 74th percentile among 102 sector filers · read for its customers

From the record

Twist Bioscience Corporation's standing among 102 graded names in its industry family: revenue of $377 million in fiscal 2025 ranks in the top 17% by size; a net margin of -20.6% ranks in the top 27%; revenue growth of 22.8% a year over the last 3 filed years ranks in the top 33% (its annual reports).

What it rests on

  • revenue against the family$377Mtop 17% of its family
  • net margin-20.6%top 27% of its family
  • three-year revenue growth22.8%top 33% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Leadership

as filed
8.1/10

What are the people in charge doing?

top 19% of 110 in its family for leadership; chief executive since 2018.

weight 33% of this tense · 81st percentile among 110 sector filers · read for its shareholders

From the record

Twist Bioscience Corporation's leadership, from its insiders' filings and its current reports: the chief executive on the record is Leproust, Emily M. (Chief Executive Officer, as filed), filing under that title since 2018-10-30, 8 years (top 20% of its family); the 13 officers and directors filing in the last fifteen months have been on the record a median of 8 years (top 12%); 4 officer or director changes were reported on Form 8-K since 2023-11-13, against the 13 people in charge now (top 26%; fewer changes for each person reads higher) (the Form 4 record, its Form 8-K reports). Years count from a person's first filing in the SEC's data sets, which begin in 2006, so each is a floor.

What it rests on

  • officer and director changes on Form 8-K, against the people in charge4 in three years among 13 peopletop 26% of its family
  • the median years the people in charge have filed8.0 yearstop 12% of its family
  • the chief executive's years on the record8.0 yearstop 20% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

▶ Future

What are they set up to do next?

4.4/1040% of the headline grade · 3 of 3 filed

Room to expand

as filed
4.3/10

How much room does it have to grow?

bottom 44% of 92 in its family for room to expand.

weight 33% of this tense · 44th percentile among 92 sector filers · read for itself

From the record

Twist Bioscience Corporation's room to grow, from the newest filed statements (fiscal 2025): cash of $185 million against no long-term debt tagged leaves 28.9% of its assets as net cash, top 48% of its family; cash from operations less capital spending is -20.1% of revenue (top 24%); a gross margin of 50.7% (bottom 29%); research spending of 21.3% of revenue (bottom 18%) (its annual report).

What it rests on

  • cash less debt against assets28.9%top 48% of its family
  • cash from operations less capital spending against revenue-20.1%top 24% of its family
  • gross margin50.7%bottom 29% of its family
  • research spending against revenue21.3%bottom 18% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Growth drivers

as filed
3.8/10

What could actually drive growth from here?

bottom 38% of 100 in its family for growth drivers.

weight 45% of this tense · 38th percentile among 100 sector filers · read for its customers

From the record

Twist Bioscience Corporation's growth drivers, from the filed years to fiscal 2025: revenue grew 22.8% a year over the last three filed years against 55.9% over all 9, slowing (bottom 21% of its family); the newest year grew 20.3% (top 44%); research spending grew -12.6% a year (bottom 27%); capital spending grew -35% a year (bottom 46%) (its annual reports). Twist Bioscience Corporation reported 5 product lines in fiscal 2025: Ngs Tools at $208 million (55%), Synthetic Genes at $114 million (30%), Antibody Discovery at $23 million (6%), and 2 more; 4 of 5 grew against the year before (its annual report).

What it rests on

  • three-year growth against the whole span-33.2 points a yearbottom 21% of its family
  • the newest year's revenue growth20.3%top 44% of its family
  • three-year growth of research spending-12.6%bottom 27% of its family
  • three-year growth of capital spending-35.0%bottom 46% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

Expectations vs reality

as filed
5.7/10

Did its newest year beat what its own record pointed to?

top 43% of 72 in its family for expectations against reality.

weight 22% of this tense · 57th percentile among 72 sector filers · read for its shareholders

From the record

Twist Bioscience Corporation's newest year against its own record: revenue of $377 million in fiscal 2025 came in 2.9% below the $388 million its prior three years' pace pointed to (bottom 43% of its family); net income of $78 million against a prior three-year average of $210 million (top 25%); a net margin of -20.6% against -85.7% before (top 47%) (its annual reports).

What it rests on

  • revenue against the prior three years' pace-2.9%bottom 43% of its family
  • net income against the prior three years' average+63%top 25% of its family
  • net margin against its prior average+65.1 pointstop 47% of its family

A production reading, recomputed from the filings on every data build, read from EDGAR Nov 13, 2026.

The grade is the company against its own industry, from its filings. It is not a view on the share price. How the grade is made

SI Assistanton TWST · research, not advice