OPKO Health, Inc. (OPK)
Nasdaq: OPK · Pharmaceutical Preparations · Miami, FL · filing with the SEC since 1996
Who owns OPKO Health, Inc.
As filed with the SECHolders of 5% or more
2
Frost Phillip Md Et Al holds 34.1% of Common Stock, par value $0.01 per share, as its SCHEDULE 13D/A filed Jul 1, 2026 says.
Directors and officers
10
report now, of 23 people on the record since 2006. Their holdings as a group are not read here.
Institutions as a whole
n/a
The record does not read the share held by managers that file Form 13F, so none is printed and no split of the rest is estimated. What it holds is the 2 named at left.
Holders of 5% or moreshare of the class, as filed
Frost Phillip Md Et Al
SCHEDULE 13D/A · filed Jul 1, 2026 · Common Stock, par value $0.01 per share · 32.8% in Oct 1, 2025
Rubric Capital Management LP
SCHEDULE 13G/A · filed Jul 9, 2025 · Common Stock, par value $0.01 per share
Hsiao Jane Ph D
SCHEDULE 13D/A · filed Apr 3, 2025 · Common Stock, par value $0.01 per share · reported falling below 5%
What OPK reports owning in othersstakes of 5% or more, and other ties
Cocrystal Pharma, Inc. COCP
SCHEDULE 13D · filed Aug 7, 2026 · Common Stock, par value $0.001 per share
Entera Bio Ltd. ENTX
SCHEDULE 13G · filed Apr 2, 2025 · Ordinary Shares Nominal value of NIS 0.0000769 per share
Other ties the annual report names
Eirgen
An entity · consolidated entity · owns, named in the 10-K filed Feb 26, 2026
Leader Med
An investee · investee · invested in, named in the 10-K filed Feb 26, 2026
14 subsidiaries in 7 countries, from the list filed with the 10-K filed Feb 26, 2026.
Insider tradesForm 4
2sales
33purchases
0sales on a scheduled plan
1people selling
$0sold, in dollars
$3.0Mbought, in dollars
Open-market trades on Form 4 from Nov 5, 2025 to Nov 5, 2026. A scheduled plan is a selling program set in advance under SEC rule 10b5-1. The trades are listed as filed and do not feed the grade.
By calendar yearSoldBought
2026 runs to Nov 5, 2026. Dollars as filed, summed by the transaction date.
People who traded in the window2 of 24 on the roster
| Person | Role as filed | Sales | Sold | On a plan | Buys | Bought |
|---|---|---|---|---|---|---|
| Frost Gamma Investments Trust | CEO & Chairman | 0 | $0 | 0 | 32 | $3.0M |
| Paganelli John A | Interim CEO, COB | 2 | $0 | 0 | 1 | $0 |