Patents
US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026
1,313 patents granted to the 9 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to Vertex Pharmaceuticals Incorporated’s names, not what it holds today.
Patents granted
1,313
1,283 utility, 24 design, 6 reissue, 1976 to Dec 31, 2025
Granted in 2025
47
Against 40 in 2024 and 33 in 2023
Applications published
1,245
71 of them in 2025
Names they are printed under
9
its own name, a subsidiary
By yearGrantedApplications published
'11'12'13'14'15'16'17'18'19'20'21'22'23'24'25
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Pharmaceuticals80
Organic fine chemistry55
Biotechnology36
Medical technology15
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name9 counted
Vertex Pharmaceuticals Incorporated its own name
US, as the owner printed on each patent. 2 more under the same name are not counted (printed in GB)
1,155 granted
750 publishedVertex Pharmaceuticals Incorporated its own name
named as the applicant on its applications, in US. 1 more under the same name are not counted (printed in MA)
0 granted
334 publishedViaCyte, Inc. a subsidiary
US, as the owner printed on each patent
109 granted
72 publishedALPINE IMMUNE SCIENCES, INC. a subsidiary
US, as the owner printed on each patent
25 granted
44 publishedViaCyte, Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
26 publishedVertex Pharmaceuticals (San Diego) LLC a subsidiary
US, as the owner printed on each patent
19 granted
3 publishedVertex Pharmaceuticals (Europe) Limited a subsidiary
GB, as the owner printed on each patent
5 granted
5 publishedVertex Pharmaceuticals (Europe) Limited a subsidiary
named as the applicant on its applications, in GB
0 granted
7 publishedAlpine Immune Sciences, Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
4 published
Newest grantseach row opens the USPTO’s own copy
| Granted | Patent | Title | Field | Owner as printed |
|---|
| Dec 30, 2025 | 12,508,231 | Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
| Dec 23, 2025 | 12,503,439 | Heteroaryl compounds for the treatment of pain | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Dec 23, 2025 | 12,502,376 | Pyrano[4,3-b]indole derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD) | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
| Dec 16, 2025 | 12,497,614 | Compositions and methods for editing beta-globin for treatment of hemaglobinopathies | Biotechnology | Vertex Pharmaceuticals Incorporated |
| Dec 9, 2025 | 12,492,388 | Materials and methods for treatment of hemoglobinopathies | Biotechnology | Vertex Pharmaceuticals Incorporated |
| Dec 2, 2025 | 12,486,312 | Immunomodulatory proteins with tunable affinities | Pharmaceuticals | ALPINE IMMUNE SCIENCES, INC. |
| Nov 4, 2025 | 12,458,635 | Pharmaceutical composition and administrations thereof | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
| Oct 14, 2025 | 12,442,020 | Materials and methods for treatment of pain related disorders | Biotechnology | Vertex Pharmaceuticals Incorporated |
| Oct 14, 2025 | 12,441,703 | Carboxamides as modulators of sodium channels | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Oct 14, 2025 | 12,440,481 | Esters and carbamates as modulators of sodium channels | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
Newest applications publishedan application is a clue, never a plan
| Published | Application | Title | Field | Owner as printed |
|---|
| Dec 25, 2025 | 2025/0388543 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
| Dec 25, 2025 | 2025/0388541 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Dec 11, 2025 | 2025/0376462 | ISLET CELL MANUFACTURING COMPOSITIONS AND METHODS OF USE | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
| Dec 4, 2025 | 2025/0366970 | 3-DIMENSIONAL LARGE CAPACITY CELL ENCAPSULATION DEVICE ASSEMBLY | Medical technology | ViaCyte, Inc. |
| Nov 27, 2025 | 2025/0361211 | DEUTERATED CFTR POTENTIATORS | Organic fine chemistry | Vertex Pharmaceuticals (Europe) Limited |
| Nov 20, 2025 | 2025/0353836 | N-(HYDROXYALKYL (HETERO)ARYL) TETRAHYDROFURAN CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Nov 20, 2025 | 2025/0353834 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED TETRAHYDROFURAN MODULATORS OF SODIUM CHANNELS | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Nov 6, 2025 | 2025/0340574 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Nov 6, 2025 | 2025/0340568 | SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION | Organic fine chemistry | Vertex Pharmaceuticals Incorporated |
| Oct 30, 2025 | 2025/0332151 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | Pharmaceuticals | Vertex Pharmaceuticals Incorporated |
What it applied for, 2024 to 2025: Pharmaceuticals 49 · Biotechnology 35 · Organic fine chemistry 29 · Medical technology 10 · Analysis of biological materials 1 · Surface technology, coating 1.
A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.