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Xilio Therapeutics, Inc. (XLO)

Nasdaq: XLO · Pharmaceutical Preparations · Waltham, MA · filing with the SEC since 2021
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Grade4.7
◀ Past 4.1● Present 4.1▶ Future 5.9
4 est.
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Patents

US patents through Dec 31, 2025 · PatentsView, from the USPTO’s Open Data Portal · read Oct 27, 2026

8 patents granted to the 2 names below, as the owner printed on each patent when it was granted. A later sale, a lapse or an expiry is not read, so this is what was granted to Xilio Therapeutics, Inc.’s names, not what it holds today.

Patents granted
8
8 utility, 1976 to Dec 31, 2025
Granted in 2025
3
Against 1 in 2024 and 3 in 2023
Applications published
21
4 of them in 2025
Names they are printed under
2
a subsidiary
By yearGrantedApplications published
'21'22'23'24'25
Each pair is one calendar year. Applications are published about eighteen months after filing, so the newest years read low.
What they are aboutgrants since 2021
Biotechnology5
Pharmaceuticals3
The main technology area of each patent, in the World Intellectual Property Organization’s 35 fields.
Under which name2 counted
Xilio Development, Inc. a subsidiary
named as the applicant on its applications, in US
0 granted
18 published
Xilio Development, Inc. a subsidiary
US, as the owner printed on each patent
8 granted
3 published
Newest grantseach row opens the USPTO’s own copy
GrantedPatentTitleFieldOwner as printed
Oct 7, 202512,435,142Anti-CTLA4 antibodies and methods of use thereofPharmaceuticalsXilio Development, Inc.
Aug 12, 202512,384,845Activatable masked anti-CTLA4 binding proteinsPharmaceuticalsXilio Development, Inc.
Apr 22, 202512,280,120Tumor-specific cleavable linkersPharmaceuticalsXilio Development, Inc.
Jan 9, 202411,866,476Masked IL-2-Fc fusion polypeptidesBiotechnologyXilio Development, Inc.
Nov 28, 202311,827,686Masked cytokine polypeptidesBiotechnologyXilio Development, Inc.
Nov 28, 202311,827,685Masked cytokine polypeptidesBiotechnologyXilio Development, Inc.
Aug 8, 202311,718,655Masked interleukin-12 polypeptidesBiotechnologyXilio Development, Inc.
Jul 6, 202111,053,294Masked cytokine polypeptidesBiotechnologyXilio Development, Inc.
Newest applications publishedan application is a clue, never a plan
PublishedApplicationTitleFieldOwner as printed
Sep 18, 20252025/0289889ACTIVATABLE MASKED ANTI-CTLA4 BINDING PROTEINSPharmaceuticalsXilio Development, Inc.
Aug 7, 20252025/0250314MASKED IL-2 CYTOKINES AND METHODS OF USE THEREOFBiotechnologyXilio Development, Inc.
Mar 27, 20252025/0101075MASKED IL-2 CYTOKINES AND METHODS OF USE THEREOFBiotechnologyXilio Development, Inc.
Mar 20, 20252025/0092109VHH MASKED CYTOKINES AND METHODS OF USE THEREOFPharmaceuticalsXilio Development, Inc.
May 2, 20242024/0141007ENGINEERED CLEAVABLE CARRIERS AND METHODS OF USE THEREOFBiotechnologyXilio Development, Inc.
Nov 16, 20232023/0365641TARGETED CYTOKINES AND METHODS OF USE THEREOFBiotechnologyXilio Development, Inc.
Oct 19, 20232023/0331799MASKED IL-15 CYTOKINES AND THEIR CLEAVAGE PRODUCTSBiotechnologyXilio Development, Inc.
Jul 27, 20232023/0235006Masked Cytokine PolypeptidesBiotechnologyXilio Development, Inc. · patent 11,866,476 granted from it
May 25, 20232023/0159603MASKED IL-12 CYTOKINES AND THEIR CLEAVAGE PRODUCTSPharmaceuticalsXilio Development, Inc.
May 18, 20232023/0151072MASKED IL-2 CYTOKINES AND THEIR CLEAVAGE PRODUCTSPharmaceuticalsXilio Development, Inc.
What it applied for, 2024 to 2025: Biotechnology 3 · Pharmaceuticals 2.

A patent is counted where the owner printed on it when it was granted carries the company’s own name, a former name, the name of a subsidiary its annual report lists, or its own name with a patent-holding phrase (Technology Licensing, Intellectual Property and the like), once the legal form, case and punctuation are set aside, and prints a country that name counts in. PatentsView’s data are published under the Creative Commons Attribution 4.0 licence. Source: PatentsView's granted patents and pre-grant publications, disambiguated, from the USPTO's Open Data Portal, through Dec 31, 2025, read Oct 27, 2026.

SI Assistanton XLO · research, not advice