Company Analysis

Zymeworks Inc. (ZYME)

Nasdaq: ZYME · Pharmaceutical Preparations · Middletown, DE · filing with the SEC since 2022
Grade5.1
◀ Past 5.8● Present 5.1▶ Future 4.4
1 est.
The companyfiscal 2025, as filed
Revenue$106M+38.9%
Net income-$81.1M+33.9%
Earnings per share$-1.08+33.3%
Operating cash flow-$33.0M+70.0%
Cash$41.2M-37.7%
Debtn/a
Shareholders’ equity$269M-20.7%
Shares, diluted75.4M-0.6%
Return on equity-30.2%
The recordfrom its filings
Filings in 202666
Newest filingNov 9 · 10-Q
Annual reportMar 2, 2026
Quarterly reportNov 9, 2026
Next report due10-K by Mar 31
Insider sales, 12 months$5.0M
Insider buys, 12 months$0.00
Patents granted17
Filer categoryNon-accelerated filer<br>Smaller reporting company
Trailing twelve months to Sep 2026Revenue $266MNet income $43.3MCash from operations -$112Mthe four newest filed quarters added
Left: the newest annual report, with the change on the year before. Right: counted from the company's own filings with the SEC.
Revenue and net income by fiscal yearRevenueNet income
202122232425
As filed, in USD. Nothing here is a forecast.

The company now

Zymeworks licensed its DLL3 cancer drug candidate ZW209 to Roche on 22 October 2026 1. Roche is to pay $55.0 million upfront and $40.0 million when a Phase Ib trial starts, plus up to $718 million in milestones, or up to $813 million in all (computed) 1.

The license starts only after United States antitrust clearance 1. Roche pays for the opening human trial that Zymeworks will run, and Zymeworks is eligible for royalties from the high single digits to the mid-teens on any sales 1.

The FDA approved Ziihera, a cancer antibody Zymeworks discovered and its partner Jazz sells, for first-line HER2-positive stomach and esophageal cancer on 25 August 2026 517. That earned Zymeworks a $250 million milestone payment 5.

On 23 September 2026 Zymeworks completed its purchase of Theravance Biopharma, adding YUPELRI, a medicine promoted in hospitals, to its royalty income 34. The company then said it expects 2026 revenue of $278 million to $292 million 4.

The latest quarterly report on file covers the three months to 30 June 2026, before these deals, when revenue was $4.6 million 7. Third-quarter results are due on 9 November 2026 11.

As of Nov 4, 2026. Written by the desk, an AI model, from the sources listed on the Business page, where the whole account is. Nothing here is advice.

Newer filings are on file since this was written; an update is queued.

News

Nov 9, 2026 · SEC EDGAR · Form 10-Q
Quarterly report
Open the filing on sec.gov
Nov 9, 2026 · SEC EDGAR · Form 8-K
Results released
Open the filing on sec.gov
Oct 26, 2026 · SEC EDGAR · Form DEFA14A
Extra proxy material
Open the filing on sec.gov
Oct 26, 2026 · SEC EDGAR · Form DEF 14A
Proxy statement
Open the filing on sec.gov
Oct 23, 2026 · SEC EDGAR · Form 8-K
Current report
Open the filing on sec.gov
Oct 9, 2026 · SEC EDGAR · Form 4
Insider trade report
Open the filing on sec.gov
An outside story is shown by its headline, its source and its link only. The SI reads the page when you ask it to break one down.
SI Assistanton ZYME · research, not advice